Category: Prostate Cancer

  • UroToday – Percent Tumor Involvement and Risk of Biochemical Progression After Radical Prostatectomy

    From UroToday: We examined the association between percent tumor involvement in the radical prostatectomy specimen and the outcome measures of pathological stage and biochemical progression using multivariate logistic regression and Cox proportional hazards analysis, respectively, in 2,220 patients from the Duke Prostate Center radical prostatectomy database. This was a study that showed that if you…

  • Determinants of Long-Term Retention of Prostate Cancer Patients in Active Surveillance Management Programs

    From Urotoday and the AUA Of the 2134 PCa cases, 169 (7.9%) had AS as their initial management. Of the 169 AS cases, 89 (53%) remained untreated throughout follow-up (mean 7.1 years) and the remaining 47% received treatment an average of 3.1 years post-diagnosis. Significant predictors of eventual active treatment in multivariate models included younger…

  • Vitamin D doesn’t cut prostate cancer risk

    Source Reuters U.S. National Cancer Institute researchers set out to see if vitamin D might protect against prostate cancer, the second most frequently diagnosed cancer in men worldwide. They tracked vitamin D concentrations in the blood of 749 men diagnosed with prostate cancer and 781 men who did not have the disease. They found no…

  • Surgical experience affects prostate cancer control ‘regardless of risk’

    From MedWire News – Oncology – Prostate cancer control after radical prostatectomy improves with increasing surgeon experience, regardless of patients’ risk, say US scientists who suggest that the primary reason for recurrence in low-risk patients is inadequate surgical technique. The team, led by Eric Klein from the Cleveland Clinic in Ohio, previously discovered that open…

  • Median Lobe in Robot-Assisted Radical Prostatectomy: Evaluation and Management

    UroToday – The surgical margins were similar between the two groups. No significant difference was found in the postoperative urinary bother score or the interval to social or perfect continence between the two groups. The results of this study have shown that the presence of a median lobe does not alter the outcomes in patients…

  • – Oncology – High saturated fat diet linked to postop biochemical failure

    From MedWire News Among prostatectomy patients, those with diets high in high saturated fat (HSF) are almost twice as likely to experience biochemical failure as those who consume a low saturated fat (LSF) diet, say US scientists. Several studies have indicated that obesity is associated with an increased risk of biochemical failure after treatment with…

  • Active Surveillance for Prostate Cancer Patients

    From Medscape May 12, 2008 — The urine test for the PCA3 gene, already marketed for use in diagnosing prostate cancer, could also be useful in prognostication. It might have clinical application in selecting men with low-grade and low-volume tumors who would be suitable candidates for active surveillance, say researchers writing in the May issue…

  • Newer Prostate Cancer Treatment Similar to Traditional Surgery

    From Washington Post.com “This reaffirms what many other manuscripts have shown, if you go to an individual who has experience, who does this on a consistent basis, your outcomes will be better,” said Dr. Ihor S. Sawczuk, chief of urologic oncology for the Cancer Center at Hackensack University Medical Center, in New Jersey. “If you…

  • Biomarker predicts malignancy potential of prostate lesions –

    From Urology Times Spanish researchers have found a means of distinguishing between high-grade prostatic intraepithelial neoplasia (HGPIN) lesions destined to become cancerous and those that will remain benign, which may spare patients the discomfort and inconvenience of unnecessary needle biopsies, according to a study in Clinical Cancer Research (2008; 14:2617-22). This is the first studay…