Tag: watchful waiting

  • 5-ARI delays prostate cancer progression in men with low-risk disease – ModernMedicine

    The 5-alpha-reductase inhibitor dutasteride Avodart appears to delay disease progression and the initiation of active treatment in men with low-risk, localized prostate cancer, results of a 3-year international clinical trial indicate.Treatment with dutasteride also reduces cancer-related anxiety, study authors found.”The results prove that using active surveillance plus dutasteride is a viable, safe, and effective treatment…

  • Determinants of Long-Term Retention of Prostate Cancer Patients in Active Surveillance Management Programs

    From Urotoday and the AUA Of the 2134 PCa cases, 169 (7.9%) had AS as their initial management. Of the 169 AS cases, 89 (53%) remained untreated throughout follow-up (mean 7.1 years) and the remaining 47% received treatment an average of 3.1 years post-diagnosis. Significant predictors of eventual active treatment in multivariate models included younger…

  • Active Surveillance for Prostate Cancer Patients

    From Medscape May 12, 2008 — The urine test for the PCA3 gene, already marketed for use in diagnosing prostate cancer, could also be useful in prognostication. It might have clinical application in selecting men with low-grade and low-volume tumors who would be suitable candidates for active surveillance, say researchers writing in the May issue…

  • Cryosurgery better than watchful waiting for elderly?

    Straightfromthedoc: JAMA Study Confirms Prostate Cancer Treatment is Preferable over “Watchful Waiting” According to Endocare President, Chairman and CEO Craig T. Davenport: “This study offers further scientific evidence that ‘watchful waiting’ may not be the best option for many patients, particularly when there are effective, minimally invasive treatments like cryoablation available. Based on the results…

  • Survival advantage with surgery for elderly patients with prostate cancer?

    JAMA — Survival Associated With Treatment vs Observation of Localized Prostate Cancer in Elderly Men, December 13, 2006, Wong et al. 296 (22): 2683 Conclusions This study suggests a survival advantage is associated with active treatment for low- and intermediate-risk prostate cancer in elderly men aged 65 to 80 years. Because observational data cannot completely…

  • Watchful waiting vs. definitive therapy

    UroToday – What is the Best Approach for Screen-Detected Low Volume Cancers? What is the Best Approach for Screen-Detected Low Volume Cancers? BETHESDA, MD (SUO 7th Annual Meeting – December 1-2, 2006:NIH) – In a session moderated by Dr. Eric Klein, Cleveland Clinic, Dr. Laurence Klotz, University of Toronto presented the “The Case for Observation”.…

  • Watchful waiting for prostate cancer

    UroToday – European Urology – Watching the Face of Janus- Active Surveillance as a Strategy to Reduce Overtreatment for Localised Prostate Cancer A good abstract by Swedish urologists that addresses many of the issues for watchful waiting. It points out that the best candidates have a small amount of gleason 6 cancer. Most men did…