Lower PSA Predicts Favorable Salvage Radiotherapy Outcomes – Renal and Urology News

The overall median follow-up was 63.5 months. The 5-year BCR-free survival rate was 58.2% for the cohort overall and 76.2% for the 118 patients 55.7% who had early salvage RT, defined as RT started when the PSA level was 0.5 ng/mL or less, the investigators reported online in PLoS One

via Lower PSA Predicts Favorable Salvage Radiotherapy Outcomes – Renal and Urology News.

When patients have a PSA that rises over 0.1 after robotic prostatectomy, they likely have recurrent prostate cancer somewhere. This study shows that patients treated with salvage XRT (external beam radiotherapy) had better results if the treatment was started below a PSA of 0.5.

Personally, in the patients who are good candidates for salvage XRT, I prefer to start the radiation after the PSA goes higher than 0.2 and sometimes lower.

Added Radiation to ADT May Improve Survival – Renal and Urology News

Men with locally advanced prostate cancer (PCa) have a better chance of survival when they add radiation therapy (RT) to their hormone therapy, according to research presented at the 52nd annual meeting of the American Society for Radiation Oncology.

via Added Radiation to ADT May Improve Survival – Renal and Urology News.

This is another study that finds a survival advantage in adding radiation therapy to hormonal therapy in advanced prostate cancer.  Traditionally, urologists treated these patients with hormonal therapy only since radiation was not curative.

Newer studies are showing that external beam radiation added to hormonal therapy helps people live longer.  I think this is because radiation therapy is safer than it was in the past and treating the primary tumor may help prevent future metastases.

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