Notice: Function _load_textdomain_just_in_time was called incorrectly. Translation loading for the health-check domain was triggered too early. This is usually an indicator for some code in the plugin or theme running too early. Translations should be loaded at the init action or later. Please see Debugging in WordPress for more information. (This message was added in version 6.7.0.) in /var/www/wp-includes/functions.php on line 6121
You probably should perform a repeat biopsy after high grade pin (HGPIN) – The Robotic Surgeon – Domenico Savatta, M.D.

You probably should perform a repeat biopsy after high grade pin (HGPIN)

IngentaConnect The incidence of high-grade prostatic intraepithelial neoplasia a…:

beige_quote.bmpCONCLUSION:
Identifying multifocal HGPIN on first saturation biopsy is associated with an overall cancer detection rate of 80% on repeat 10-12-core biopsy. Although there were few patients, the detection of multifocal HGPIN warrants additional searches for concurrent invasive carcinoma by repeated biopsy.

The diagnosis of high grade PIN is an area that once required a repeat prostate biopsy. Recently, with an increase the number of biopsies that are done initially, there has been feelings that patients who only have high grade PIN do not need another biopsy. This article suggests that these patients should have a repeat biopsy. I believe follow-up with a PSA is a recent option in older patients with high grade PIN.